Friday, 30 August 2013

Dyslipidemia is a lipoprotein metabolism disorder characterized by abnormal amount of lipoprotein (LDL and HDL) concentrations in blood. It is usually caused by genetic factors, secondary factors or a combination of both kinds of factors. High density lipoproteins (HDL) are also known as good cholesterol and higher levels of these help reduce the risk of cardiovascular diseases. Higher levels of low density lipoproteins (LDL) or bad cholesterol are associated with the risk of heart attacks and strokes. 

The abnormal levels of cholesterol and triglycerides are capable of producing three forms of dyslipidemia namely, hypertriglyceridemia, hypercholesterolemia and a combination of both. Dyslipidemia is one of the major causes for the occurrence of cardiovascular diseases. Appropriate drug therapy against dyslipidemia can be selected based on the detection of varying concentrations of specific lipoproteins in the blood. The treatment approach adopted by physicians starts with non-drug interventions, which includes lifestyle modifications and exercise followed by pharmacotherapy which includes the use of lipid lowering drugs. 

The seven major classes of lipid lowering drugs used in the treatment of dyslipidemia are bile-acid sequestrants, nicotinic acid, HMG-CoA reductase inhibitors (statins), cholesterol modulators, fibric acid derivatives, cholesterol absorption inhibitors and combination products. Statins are the most widely used drugs to treat dyslipidemia. The dyslipidemia market can be segmented by the various drug classes mentioned above and by geography.  

The major factors influencing the growth of this market are sedentary lifestyle, higher inclination towards junk food, increasing incidence of cardiovascular diseases across the globe and associated risks. Patent expirations and high genericization may mask the growth of this market. With the patent expiration of Pfizer’s Lipitor, Merck’s Zocor and Bristol-Myers Squibb’s Pravachol, the dyslipidemia market is expected to experience a decline in sales of branded formulations and in turn decline in overall growth of this market. Some of the major players in this market are Pfizer, Inc., Merck & Co, Inc., Bristol-Myers Squibb, Novartis AG, AstraZeneca PLC and Abbott Laboratories. 

More reports on Pharmaceuticals market:

This research report analyzes this market depending on its market segments, major geographies, and current market trends. Geographies analyzed under this research report include 
  • North America 
  • Asia Pacific 
  • Europe
  • Rest of the World  
This report provides comprehensive analysis of 
  • Market growth drivers 
  • Factors limiting market growth
  • Current market trends 
  • Market structure
  • Market projections for upcoming years 
This report is a complete study of current trends in the market, industry growth drivers, and restraints. It provides market projections for the coming years. It includes analysis of recent developments in technology, Porter’s five force model analysis and detailed profiles of top industry players. The report also includes a review of micro and macro factors essential for the existing market players and new entrants along with detailed value chain analysis.

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